

Generative Biology Institute
Building a faculty of leading researchers to tackle the key challenges in making biology engineerable and unlock its potential to benefit humanity.
Dr Fabian Rehm
Fabian obtained his PhD from the University of Queensland and was a postdoc at the CMRC-LMB in Cambridge where he co-led genome synthesis work and has developed a new orthogonal replication system for accelerated evolution.
At GBI Fabian aims to develop approaches for the accelerated evolution of multigene systems, including biosynthetic pathways and molecular machines, where multiple components may need to be evolved simultaneously to generate a functional system that carries out a task.
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The GBI team aims to unlock the blueprint of life, enabling the rapid and scalable synthesis of entire genomes with newfound precision. Success would enable the identification and potential creation of DNA sequences that could generate biological systems designed to perform specific functions. These new DNA construction techniques could have a wide range of commercial applications, including designing more efficient crops with higher yields or finding personalised cell therapies and vaccines. Specially engineered cell processes could also support new biodegradable materials to help tackle the problems of climate change.
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