PhD Projects in Economics

Structural Macroeconomic Models of Healthy  Ageing

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Project Summary

The aim is to create macroeconomic models that quantify the impact of prevention, ageing, and medical innovation on the economy—including implications for fiscal sustainability, labour supply, productivity, and even monetary policy—by developing and calibrating general-equilibrium, heterogeneous-agent frameworks in which both life expectancy and healthy-life expectancy are endogenous outcomes of preventive investment, health R&D, and labour-market dynamics.
The research will:

  • Quantify macroeconomic feedbacks of chronic‑disease burdens on growth, capital accumulation and fiscal sustainability.
  • Analyse the distributional consequences of ageing, health investment, and medical innovation—including how chronic disease, prevention, and access to new technologies shape inequality in health, income, and lifetime welfare.
  • Identify optimal retirement and labour‑force‑participation policies when older workers face rising morbidity risk but possess valuable human capital.
  • Compute the distribution of willingness‑to‑pay for prevention across the wealth‑ and income‑space, showing how policy design (e.g. subsidies vs mandates) can maximise welfare and affect income and/or wealth inequality.
  • Embed directed medical R&D—where firms allocate research effort across disease areas—in order to derive endogenous paths of medical‑progress‑based growth and to study how prevention policies reshape innovation incentives.

Why it matters
Governments confront intertwined challenges: exploding chronic‑disease costs, shrinking working‑age populations and uneven access to preventive care. Existing macro models typically treat health as exogenous or focus only on mortality. A framework that links healthy ageing, productive ageing and directed innovation is essential for:

  • Making the general‑equilibrium case for preventive spending
  • Guiding the design of retirement ages and flexible‑work schemes
  • Prioritising public R&D subsidies toward high‑impact disease areas
  • Informing health technology appraisals with state‑contingent (e.g. across income or wealth distribution) welfare metrics rather than average cost‑per‑QALY figures.

Why EIT is the place
EIT uniquely combines secure access to linked electronic health records, earnings, and pension data—critical for empirical calibration—with GPU/CPU clusters for solving high‑dimensional equilibrium systems. Interaction with EIT’s prevention, clinical and AI/data‑science teams ensures biologically realistic health processes and cutting‑edge numerical methods, while Oxford’s economics and policy faculties provide a rich intellectual environment for macro‑public‑finance questions.

Potential Supervisors  

  • Supervisors are to be confirmed

Skills Recommended

  • Graduate micro & macro theory (dynamic optimisation, GE)
  • Solid quantitative background in maths/stats (stochastic calculus, numerical methods)
  • Programming experience (Python, Julia or MATLAB)
  • Motivation to work across economics, data science and health domains

Skills to be Developed

  • Continuous‑time and discrete‑time heterogeneous‑agent modelling
  • Sparse‑matrix & GPU‑accelerated solvers for HJB–KFE systems
  • Calibration & validation with linked administrative micro‑data
  • Welfare‑analysis techniques for health‑economics and public‑finance audiences
  • Policy‑simulation and translation skills for decision‑makers

University DPhil Courses 

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Supervisors

We are bringing together experts from across the globe, with a shared drive to create lasting impact.

Director of the Oxford Vaccine Group, Ashall Professor of Infection & Immunity

Professor Sir Andrew Pollard

Correlates of Immunity

Director of the Oxford Vaccine Group in the Department of Paediatrics at the University of Oxford.

Principal Scientist, Pathogen Program & Member of the Board of Directors

Professor Gil McVean

Principal Scientist, Pathogen Program & Member of the Board of Directors. Professor of Statistical Genetics at the Department of Statistics and the Nuffield Department of Medicine, University of Oxford.

Principal Scientist, Plant Biology Institute & Member of the Board of Directors

Professor Steve Kelly

Principal Scientist Plant Biology Institute & Member of the Board of Directors at EIT. Professor of Plant Sciences and Senior Research Fellow of the Queens College, University of Oxford.

Executive Director & Principal Scientist

Dr Danilo Jimenez Rezende

AI & Robotics Institute

Executive Director & Principal Scientist for AI & Robotics at EIT. Former Director at Google DeepMind.

Executive Director & Executive Vice President

Dr Matej Macak

AI & Robotics Institute

Executive VP, AI & Robotics at EIT. Chief Technologist at Every Cure.

Principal Scientist, Economics

Professor Andrew Scott CBE

Economics

Principal Scientist of Economics, Economics Professor at University of Oxford. Research covers economics and longevity in aging societies.

Executive Director & Principal Scientist, Materials & Devices for Life Sciences

Professor Hagan Bayley

Materials & Devices for Life Sciences

Professor of Chemical Biology at the University of Oxford. Founder of Oxford Nanopore Technologies. Fellow of the Royal Society.

Founding Director, Generative Biology Institute

Professor Jason Chin

Generative Biology Institute

Founding Director, of the Generative Biology Institute (GBI) and Professor of Chemistry and Chemical Biology at the University of Oxford.

Research Scientist

Dr Ben Chamberlain

AI & Robotics Institute

Research Scientist in the AI & Robotics Institute at EIT. Previously held leadership roles at biotechs Isomorphic Labs and Charm Therapeutics.

Senior Director Device Science

Dr James Clarke

Senior Director of Product Science in the Pathogen Project at EIT.

Principal Investigator

Dr Jérôme Zürcher

Generative Biology Institute

Principal Investigator within GBI at EIT. Former junior research fellow at Trinity College, Cambridge and visiting researcher at the Innovative Genomics Institute at UC Berkeley.

Group Leader

Dr Linna Zhou

Materials & Devices for Life Sciences
Program Co-Lead

Professor Daniela Ferreira

Correlates of Immunity

Professor of Mucosal Immunology and Vaccinology at the Oxford Vaccine Group, Paediatrics Department, University of Oxford.

Senior Director, Science Applications

Professor Justin O'Grady

Pathogen Program

Senior Director of Science Applications in the Pathogen Program at EIT. Honorary Professor at the University of East Anglia.

Senior Group Leader

Professor Yujia Qing

Materials & Devices for Life Sciences

A Senior Group Leader in the Materials & Devices for the Life Sciences program at EIT. An Associate Professor in the Department of Chemistry, University of Oxford

Staff Scientist, AMR and Applied Metagenomics

Dr Vicky Enne

Pathogen Program
Senior Group Leader, Cell Based Production

Professor Lee Sweetlove

Plant Biology Institute