PhD Projects in Economics

Measuring Health and Ageing: From Biology to Economics

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Project Summary

Health is central to individual wellbeing, economic productivity, and the sustainability of public institutions. Yet we still lack a concise, interpretable measure of health that captures both its biological and economic dimensions. The major global health challenge we now face is around age-related diseases. This project aims to develop a low-dimensional, data-driven index of health and/or ageing - a tool that distills a wide array of biological, clinical, and socioeconomic data into a small number of meaningful factors that:

  • Capture the dynamics of biological ageing and physiological resilience, and
  • Reflect an individual's functional economic capacity - their ability to work, perform essential tasks, remain in their chosen occupation, and accumulate resources over the life-course.

In doing so, the project speaks to a set of foundational questions: How do we age? What predicts resilience? What aspects of health are most important to measure - and when? By confronting these questions, the project contributes both to our understanding of intrinsic and extrinsic health and to the development of new metrics of ageing and wellbeing.

Such a measure would serve as a common framework for clinicians, economists, and policymakers to evaluate the impact of health interventions - not just in terms of added life-years or symptom relief (as in QALYs/DALYs), but in terms of people’s real-world capacity to function, earn, and participate in society.

Why it matters

  • Enables more realistic macroeconomic models of longevity, ageing, and fiscal sustainability.
  • Identifies the most impactful stages in the life-course for health or skills interventions.
  • Provides a shared outcome metric to evaluate new therapeutics, workplace policies, and social programs across disciplines.
  • Advances the ability to value health technologies based on their contribution to both healthspan and economic agency.
  • Provides policymakers with a narrative-shaping, decision-relevant metric that links health to economic capability - informing key decisions around pension design, prevention incentives, healthcare system resource allocation, and health R&D priorities, while supporting investment in interventions that extend not just life, but functional and productive years.

Why EIT is the place

EIT provides secure, linked access to electronic health records, multiomics panels, tax and pension histories - exactly the scope needed to fuse “health” and “wealth”. On‑site GPU/CPU clusters and close collaboration with EIT AI and Data‑science team supports deep learning approaches or large model training while clinical groups enable feedback on clinical/biomarker features of the index.

Potential Supervisors  

  • Supervisors are to be confirmed

Skills Recommended

  • Strong quantitative background (econometrics, statistics or applied maths)
  • Programming proficiency (Python/R)
  • Familiarity with analysis of large administrative and/or biomedical datasets
  • Enthusiasm for interdisciplinary collaboration

Skills to be Developed  

  • High‑dimensional factor modelling and representation learning
  • Causal inference with linked administrative micro‑data
  • Cloud computing and secure data‑engineering workflows
  • Translation of scientific findings into policy‑relevant welfare frameworks
  • Cross‑disciplinary communication with clinicians, biologists and data scientists

University DPhil Courses 

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Supervisors

We are bringing together experts from across the globe, with a shared drive to create lasting impact.

Director of the Oxford Vaccine Group, Ashall Professor of Infection & Immunity

Professor Sir Andrew Pollard

Correlates of Immunity

Director of the Oxford Vaccine Group in the Department of Paediatrics at the University of Oxford.

Principal Scientist, Pathogen Program & Member of the Board of Directors

Professor Gil McVean

Principal Scientist, Pathogen Program & Member of the Board of Directors. Professor of Statistical Genetics at the Department of Statistics and the Nuffield Department of Medicine, University of Oxford.

Principal Scientist, Plant Biology Institute & Member of the Board of Directors

Professor Steve Kelly

Principal Scientist Plant Biology Institute & Member of the Board of Directors at EIT. Professor of Plant Sciences and Senior Research Fellow of the Queens College, University of Oxford.

Executive Director & Principal Scientist

Dr Danilo Jimenez Rezende

AI & Robotics Institute

Executive Director & Principal Scientist for AI & Robotics at EIT. Former Director at Google DeepMind.

Executive Director & Executive Vice President

Dr Matej Macak

AI & Robotics Institute

Executive VP, AI & Robotics at EIT. Chief Technologist at Every Cure.

Principal Scientist, Economics

Professor Andrew Scott CBE

Economics

Principal Scientist of Economics, Economics Professor at University of Oxford. Research covers economics and longevity in aging societies.

Executive Director & Principal Scientist, Materials & Devices for Life Sciences

Professor Hagan Bayley

Materials & Devices for Life Sciences

Professor of Chemical Biology at the University of Oxford. Founder of Oxford Nanopore Technologies. Fellow of the Royal Society.

Founding Director, Generative Biology Institute

Professor Jason Chin

Generative Biology Institute

Founding Director, of the Generative Biology Institute (GBI) and Professor of Chemistry and Chemical Biology at the University of Oxford.

Research Scientist

Dr Ben Chamberlain

AI & Robotics Institute

Research Scientist in the AI & Robotics Institute at EIT. Previously held leadership roles at biotechs Isomorphic Labs and Charm Therapeutics.

Senior Director Device Science

Dr James Clarke

Senior Director of Product Science in the Pathogen Project at EIT.

Principal Investigator

Dr Jérôme Zürcher

Generative Biology Institute

Principal Investigator within GBI at EIT. Former junior research fellow at Trinity College, Cambridge and visiting researcher at the Innovative Genomics Institute at UC Berkeley.

Group Leader

Dr Linna Zhou

Materials & Devices for Life Sciences
Program Co-Lead

Professor Daniela Ferreira

Correlates of Immunity

Professor of Mucosal Immunology and Vaccinology at the Oxford Vaccine Group, Paediatrics Department, University of Oxford.

Senior Director, Science Applications

Professor Justin O'Grady

Pathogen Program

Senior Director of Science Applications in the Pathogen Program at EIT. Honorary Professor at the University of East Anglia.

Senior Group Leader

Professor Yujia Qing

Materials & Devices for Life Sciences

A Senior Group Leader in the Materials & Devices for the Life Sciences program at EIT. An Associate Professor in the Department of Chemistry, University of Oxford

Staff Scientist, AMR and Applied Metagenomics

Dr Vicky Enne

Pathogen Program
Senior Group Leader, Cell Based Production

Professor Lee Sweetlove

Plant Biology Institute