- Trustee, Global Challenge Initiative on The Future of Health, World Economic Forum
David Agus, MD
Founding Director and Chief Executive Officer, Ellison Institute of Technology
Professor of Medicine and Engineering, University of Southern California
Visiting Professor of Medicine, University of Oxford
310 228 6400
Dr David Agus leads a multidisciplinary team of researchers at the Ellison Institute of Technology, dedicated to the development and use of therapies and technologies to improve the care of patients and prevent disease.
Over the past twenty-five years he’s received acclaim for his innovations in medicine and contributions to new technologies, data analytics and therapeutics that change how all of us maintain optimal health and treat cancer.
His clinical responsibilities include the development of clinical trials for new drugs and treatments for cancer, supported by the National Cancer Institute and other private foundations (he has no financial ties to drug companies).
He serves in leadership roles at the World Economic Forum, among other organizations. He is a 2017 recipient of the Ellis Island Medal of Honor.
Molecular Targeted Therapy of Cancer
Physical Sciences in Oncology
Use of Genomic Profiling to Improve Cancer Care
Use of Machine Learning and Artificial Intelligence to Improve Cancer Care
1987 Molecular Biology – Princeton University, Princeton, NJ
1993-1994 – Johns Hopkins Hospital (Osler Resident in Internal Medicine), Baltimore, MD
1992 Medicine – University of Pennsylvania School of Medicine, Philadelphia, PA
1994-1996 – Memorial Sloan-Kettering Cancer Center (Fellow-Medical Oncology), New York, NY 1996-1997 – Memorial Sloan-Kettering Cancer Center (Special Fellow-Medical Oncology), New York, NY
1992-1993 – Johns Hopkins Hospital (Osler Intern in International Medicine), Baltimore, MD
Ellis Island Medal of Honor, 2017
Fellow, American College of Physicians, 2016
USC Association of Trojan Leagues Outstanding Service Annual Award, 2013
British Medical Association Commendation, Popular Medicine Book, 2012
Biotech Humanitarian Award: Selected Judge, 2009
Geoffrey Beene Foundation/GQ Magazine Rock Star of Science AwardTM, 2009
HealthNetwork Foundation Excellence Award, 2008
CaP CURE Young Investigator Award, 1998-2001
Clinical Scholar of the Sloan-Kettering Institute, 1996
American Cancer Society Clinical Oncology Fellowship Award, 1994
- Osler Housestaff Advisory Board, Johns Hopkins Department of Medicine
- Biden Cancer Initiative, Founding Board of Directors
- Contributor, CBS News
- Co-chair, Fortune Brainstorm Health
- Peres Center for Peace and Innovation, Board of Directors
The Lucky Years: How to Thrive in the Brave New World of Health. New York: Simon & Schuster, 2016. Print.
Agus M.D., David B.
A Short Guide to a Long Life. New York: Simon & Schuster, 2014. Print.
Agus M.D., David B.
The End of Illness. New York: Simon & Schuster, 2011. Print.
Agus M.D., David B.
Agus DB, Akita RW, Fox WD, Lewis GD, Higgins B, Pisacane PI, Lofgren JA, Tindell C, Evans DP, Maiese K, Scher HI, Sliwkowski MX. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell. 2002 Aug; 2(2):127-37. View in: PubMed
Hedvat M, Jain A, Carson DA, Leoni LM, Huang G, Holden S, Lu D, Corr M, Fox W, Agus DB. Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARgamma. Cancer Cell. 2004 Jun; 5(6):565-74. View in: PubMed
Agus DB, Sweeney CJ, Morris MJ, Mendelson DS, McNeel DG, Ahmann FR, Wang J, Derynck MK, Ng K, Lyons B, Allison DE, Kattan MW, Scher HI. Efficacy and safety of single-agent pertuzumab (rhuMAb 2C4), a human epidermal growth factor receptor dimerization inhibitor, in castration-resistant prostate cancer after progression from taxane-based therapy. J Clin Oncol. 2007 Feb 20; 25(6):675-81. View in: PubMed
Agus DB, Gell-Mann M. Perspective: Meeting of minds. Nature. 2012 Nov 22; 491(7425):S61. View in: PubMed
Agus DB, Michor F (2012) The sciences converge to fight cancer. Nature Physics 8(11): 773-774. View here
Agus DB: The End of Illness (2012) Simon & Schuster (Free Press), New York, NY.
Agus DB: A Short Guide to a Long Life (2014) Simon & Schuster, New York, NY.
Agus DB: The Lucky Years: how to thrive in the brave new world of health (2016) Simon & Schuster, New York, NY.
Agus DB, Gaudette É, Goldman DP, Messali A. The Long-Term Benefits of Increased Aspirin Use by At-Risk Americans Aged 50 and Older. PLoS One. 2016 Nov 30;11(11).View in: PubMed
Rawat RR, Ruderman D, Macklin P, Rimm DL, Agus DB. Correlating nuclear morphometric patterns with estrogen receptor status in breast cancer pathologic specimens. NPJ Breast Cancer. 2018 Sep 4;4:32. View in: PubMed